Coskun Lab at Georgia Tech
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CELLULAR DIFFERENTIATION

How do cells decide to change from stem cells to specific immune cells?

We use in vitro cultures and ex vivo human tissues to study cell fate selection during development from stem cells
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WHAT IS MY IDENTITY AS A CELL?

COMBINATORIAL IMMUNOTHERAPY

Would combination of checkpoint blockade enhance therapeutic outcome?

We study spatial changes in receptor polarization in tumor microenvironment
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can i use more tools to fight with cancer?

EPIGENETIC PROGRAMMING

Would epigenetic modulation make an immune cell more active toward cancers?

We explore metabolic and functional state of T-cells and B-cells as a function of epigenetic perturbations - spatial intracellular changes are used as optimization strategy.
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why does my intracellular state matter ?
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