How do we visualize multiple molecules in cells?
Using DNA biotechnology and image barcoding, we develop multiparameter imaging methods in single cells within complex tissues.
Fluorescence imaging: Using multiplex Fluorescent in situ hybridization (FISH), we profile many RNA molecules with subcellular localization. Ion beam imaging: Using imaging mass spectrometry, we screen metabolites and proteins in 3D subcellular volumes. Start Your Project Today |
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How do spatial distributions in cells change under dynamic stimuli?
Using automated microfluidics, we re-label and treat the cells with combinatorial reagents to explore spatial modulation in biological systems.
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How do we quantify high dimensional interactions across cell types with smart algorithms?
Utilizing image-data, we discover how intracellular molecules interact with each other in health and disease.
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