Coskun Lab at Georgia Tech
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BIOIMAGING

How do we visualize multiple molecules in cells?

Using DNA biotechnology and image barcoding, we develop multiparameter imaging methods in single cells within complex tissues.

Fluorescence imaging: Using multiplex Fluorescent in situ hybridization (FISH), we profile many RNA molecules with subcellular localization.

Ion beam imaging: Using imaging mass spectrometry, we screen metabolites and proteins in 3D subcellular volumes.
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Let's start multiplex imaging today

BIODYNAMICS

How do spatial distributions in cells change under dynamic stimuli?

Using automated microfluidics, we re-label and treat the cells with combinatorial reagents to explore spatial modulation in biological systems.
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shall we look at the dynamics?

BIOCOMPUTATION

How do we quantify high dimensional interactions across cell types with smart algorithms?

Utilizing image-data, we discover how intracellular molecules interact with each other in health and disease.
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why don't we turn to artificial intelligence?
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